ABSTRACT
3CL protease inhibitors has become the focus of the current research on anti-coronavirus drugs. The analysis of the patent information will help the research and innovation of such anti-coronavirus drugs. This paper analyzes the application trends of anti-coronavirus 3CL protease inhibitor-related patents, the distribution of regional status of patents, important applicants, patented technology themes, progress of key drug development and other factors. We also analyze the development of related patent technologies and aim to help domestic pharmaceutical enterprises carry out innovation and complete the strategic layout.Copyright © 2023 Chinese Journal of New Drugs Co. Ltd.. All rights reserved.
ABSTRACT
3CL protease inhibitors has become the focus of the current research on anti-coronavirus drugs. The analysis of the patent information will help the research and innovation of such anti-coronavirus drugs. This paper analyzes the application trends of anti-coronavirus 3CL protease inhibitor-related patents, the distribution of regional status of patents, important applicants, patented technology themes, progress of key drug development and other factors. We also analyze the development of related patent technologies and aim to help domestic pharmaceutical enterprises carry out innovation and complete the strategic layout.Copyright © 2023 Chinese Journal of New Drugs Co. Ltd.. All rights reserved.
ABSTRACT
Coronavirus disease 2019 (COVID-19) has accelerated the growth of the digital therapeutics (DTx) market;therefore, development strategies for new DTx products are necessary to satisfy market needs. However, data-driven methods for recommending digital healthcare technologies for novel DTx applications are scarce. We propose a technology opportunity discovery framework that recommends 1) potential technologies as new DTx products, and 2) the applicable target disorders. We applied BERTopic and PatentSBERTa to patents filed with the United States Patent and Trademark Office and calculated the score of potential technologies on the basis of their thematic characteristics with respect to their digital capabilities and similarity to DTx technologies. By identifying the target disorder of similar technologies, specific disorders were proposed that can be treated with the proposed technique. By applying the proposed framework to psychiatric disorders—one of the largest therapeutic areas of DTx, we recommend digital monitoring technologies applicable to poor breathing or sleeping patterns for cognitive impairment. Furthermore, we provide strategies to utilize the recommended digital technologies for DTx for specific disorders to facilitate a direct intervention or treatment, which can contribute to the planning of roadmaps for DTx. © 2022 Elsevier Inc.
ABSTRACT
Food science innovation depends on consumers' needs and is currently seeking functional food with health effects. Non-centrifugal cane sugar (NCS) is known for its potential health effects, but there is a lack of holistic analysis on technological advancement and socio-economic and market trends for decision-making in the development of the technology. The aim of this article was to analyse the research trends, recent patents, and market trends and niches for NCS to structure an NCS technological roadmap. Scientometric, bibliometric methods, and global and local market information on NCS were used. Comprehensive analysis of the worldwide research trends and patents on NCS processing and of the growth of the main niche markets for Colombian NCS exports in the last five years was conducted. Finally, with the information obtained, an NCS technological roadmap was structured, which can be used as a tool for planning innovation processes and supporting the development of new research using market information and new norms forged by the COVID-19 pandemic for Colombian case. Furthermore, the methodological design could be used for other NCS producer countries. Supplementary Information: The online version contains supplementary material available at 10.1007/s12355-022-01200-9.
ABSTRACT
The COVID-19 pandemic save a stringent upshot on the lives of human. The people are running in race to save themselves and the race is still on. COVID emergency has not only retarded the health of the society but also made it face the economic downfall in a severe manner. The scientists and the data analyst gave their predictions for the additional wave of infection, thus stating COVID appropriate behaviour as the medicine for the time. This health calamity provides an opportunity for cross-sector partnership of technology and science as to keep the battle fight strong, finding new roads leading to fresh solutions in health care and innovations. There is a requirement of asystematic approach for accessing the patent literature that is already available to form a research platform for further advancements. The study serves a general view of the search strategy and approach, categorization of search, database set used, websites, novelty, derivation of innovation, field of work, and the investigational dataset regarding the COVID-19 patent literature under the category of diagnosis, sanitization, personal protection and vaccine development available from December 2019 to June 2021. The patent literature provides us with the knowledge which innovation is riled fust for patent and] published documents which can be found in the database search, thus deriving the ideologies as a supplementary guidance for the advancement of innovations. Evidently, it can be concluded that our research and report can be helpful in drawing some innovative outlines with industrial applications or some others which require further interpretation with more concern. © 2022, National Institute of Science Communication and Information Resources. All rights reserved.
ABSTRACT
Two years after COVID-19 came into being, many technologies have been developed to bring highly promising bedside methods to help fight this epidemic disease. However, owing to viral mutation, how far the promise can be realized remains unclear. Patents might act as an additional source of information for informing research and policy and anticipating important future technology developments. A comprehensive study of 3741 COVID-19-related patents (3,543 patent families) worldwide was conducted using the Derwent Innovation database. Descriptive statistics and social network analysis were used in the patent landscape. The number of COVID-19 applications, especially those related to treatment and prevention, continued to rise, accompanied by increases in governmental and academic patent assignees. Although China dominated COVID-19 technologies, this position is worth discussing, especially in terms of the outstanding role of India and the US in the assignee collaboration network as well as the outstanding invention portfolio in Italy. Intellectual property barriers and racist treatment were reduced, as reflected by individual partnerships, transparent commercial licensing and diversified portfolios. Critical technological issues are personalized immunity, traditional Chinese medicine, epidemic prediction, artificial intelligence tools, and nucleic acid detection. Notable challenges include balancing commercial competition and humanitarian interests. The results provide a significant reference for decision-making by researchers, clinicians, policymakers, and investors with an interest in COVID-19 control.
ABSTRACT
Health systems, which have been under great pressure with the COVID-19 outbreak, encountered problems in accessing some urgently needed medical resources. One of these resources has been the medical ventilators needed in acute respiratory distress syndrome developing with COVID-19. As a result of the calls made, many manufacturers have modified their facilities to produce medical ventilators and the problem has been solved to a great extent. While we focus on the urgent requirement for ventilators in these troubled days of COVID-19, we do not seem to be worth discussing their technical developments. How did the countries perform in the development of novel respiratory technologies in the pre-COVID period?While patents are seen as a measure of inventive activity, we attempt to draw a general picture of patents granted in the field of medical respiratory technologies. Our study examines 27 397 respiratory patents listed in the Derwent Innovations Index database at the last 50 years and focuses on the last decade for further evaluation. In addition to the analysis of patent numbers, we identified the core ventilation technologies of the last two decades with the topic modeling technique and compared them. We used the claims section of the patents collected. It is seen that focus of ventilation patents granted between 2001 and 2010 was on oxygen, flow generation, and pressure sensors while it shifted to the pipes, measurement methods, and plates between 2011 and 2020. IEEE
ABSTRACT
Coronavirus causes significant damage to human health and the global economy. In this paper, we undertake patent analysis and data mining to systematically analyze the trend in patent applications for coronavirus detection, prevention, and treatment technologies. Our goals are to determine the correlation between typical coronavirus outbreaks and changes in patent technology applications, and to compare the research and development (R&D) progress, patent layout, and characteristics of major institutions in various countries experiencing coronavirus outbreaks. We find that the United States commenced coronavirus detection and vaccine technology R&D earlier than other countries, as it attached importance to the R&D for treatment technologies from the time of the SARS outbreak and initiated the trend of multi-party R&D, with full technology chain coverage by the government, enterprises, universities, and research institutions. China's patent applications have grown rapidly in recent years, mainly based on the R&D of research institutions and universities, although it has formed full technology chain coverage. However, the patent quality and technology global layout still need to be improved. This paper reviews the patent development trends of important coronavirus technologies, and proposes that policymakers should establish a long-term mechanism for R&D, pay attention to intellectual property protection, and deepen international technical cooperation to provide a reference for the development and application of coronavirus detection technology, vaccine technology, and treatment technology.
ABSTRACT
This work shows a patent database for Coronaviruses that provides an overview of the patenting activity and trends in focused antiviral therapy with the use of triazole based compounds, glycoprotein, and protease inhibitors as possible treatment. The patent data was obtained from Orbit Intelligence Software using a patent family structure to get a big database that could be used for built patent landscape report (PLR), market analysis, technical and competitive intelligence, and monitoring and survey of a new ideas for the treatment of coronavirus diseases. The raw data is reported in four databases, which were classified according to different items: legal status (alive, dead), 1st application year (after 2015, 2011-2015, 2006-2010, 2001-2005), and Top 5 International Patents Classifications (IPC). The main players, the investment trend, markets, geographical distribution, technology overview, technologies distribution, and patent citation are showed by this analysed data report.
ABSTRACT
BACKGROUND: Protecting intellectual property rights are important and particularly pertinent for inventions that are an outcome of rigorous research and development. While the grant of patents is subject to establishing novelty and inventive step, it further indicates the technological development and is helpful for researchers working in the same technical domain. The aim of the present research work is to map the existing work through an analysis of patent literature in the field of Coronaviruses (CoV), particularly COVID-19 (2019-nCoV). CoV is a large family of viruses known to cause illness in humans and animals, particularly known for causing respiratory infections, as evidenced in earlier times, such as in MERS i.e., Middle East Respiratory Syndrome; and SRS i.e., Severe Acute Respiratory Syndrome. A recently identified novel-coronavirus, known as COVID-19, has caused pandemic situations across the globe. OBJECTIVE: To expand the analysis of patents related to CoV and 2019-nCoV, an evaluation has been conducted by patenting trends of particular strains of identified CoV diseases by present legal status, main concerned countries via the earliest priority years and its assignee types and inventors of identified relevant patents. The global patent documents were analyzed to check the scope of claims along with focuses and trends of the published patent documents for the entire CoV family, including 2019-nCoV through the present landscape. METHODS: To extract the results, the Derwent Innovation database was used by a combination of different keystrings. Approximately 3800 patents were obtained and further scrutinized and analyzed. The present write-up also discusses the recent progress of patent applications in a period of the year 2010 to 2020 (present) along with the recent developments in India for the treatment options for CoV and 2019-nCoV. RESULTS: Present analysis showed that key areas of the inventions were the vaccines and diagnostic kits apart from the composition for the treatment of CoV. It was also observed that no specific vaccine treatments are available for the treatment of 2019-nCov; however, developing novel chemical or biological drugs and kits for early diagnosis, prevention, and disease management is the primary governing topic among the patented inventions. The present study also indicates potential research opportunities for the future, particularly to combat 2019-nCoV. CONCLUSION: The present paper analyzes the existing patents in the field of Coronaviruses and 2019-nCoV and suggests a way forward for the effective contribution in this upcoming research area. From the trend analysis, an increase in the filing of the overall trend of patent families was observed for a period of 2010 to the current year. This multifaceted analysis of identified patent literature provides an understanding of the focuses on present ongoing research and a grey area in terms of the trends of technological innovations in disease management in patients with CoV and 2019-nCoV. Furthermore, the findings and outcome of the present study offer insights for the proposed research and innovation opportunities and provide actionable information in order to facilitate policymakers, academia, research-driven institutes and also investors to make better decisions regarding programmed steps for research and development for the diagnosis, treatment and taking preventive measures for CoV and 2019-nCoV. The present article also emphasizes the need for future development and the role of academia and collaboration with industry for speedy research with a rationale.